Description

6-Bromo-4H-1,3-Benzodioxine-8-Carbaldehyde is a versatile and highly functionalized heterocyclic building block. This compound is valued for its reactive aldehyde and bromine substituents, which enable diverse synthetic transformations and the construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its benzodioxine scaffold.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, such as novel polymers or small molecules for OLEDs and sensors.
• Chemical Biology Probes: Functionalized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses serving the fine chemical and life science industries.

Basic Information

Product Name	6-Bromo-4H-1,3-Benzodioxine-8-Carbaldehyde
CAS No.	147723-32-8
Molecular Formula	C9H5BrO3
Molecular Weight	241.04 g/mol
Synonyms	6-Bromo-4H-1,3-benzodioxine-8-carboxaldehyde; 8-Bromo-6-formyl-4H-1,3-benzodioxine; 6-Bromo-8-formyl-4H-1,3-benzodioxine; 147723-32-8; 6-Bromo-4H-benzo[d][1,3]dioxine-8-carbaldehyde; 6-Bromo-1,3-benzodioxine-8-carbaldehyde; 6-Bromo-8-aldehyde-4H-1,3-benzodioxine
EINECS	Contact for details

Quality Control

Our 6-Bromo-4H-1,3-Benzodioxine-8-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.