Description

1-[4-(Bromomethyl)Phenyl]-4-Fluorobenzene is a versatile bifunctional aromatic compound featuring both a reactive bromomethyl group and a fluorinated phenyl ring. This unique structure makes it a valuable pharmaceutical intermediate and a key building block in advanced organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and liquid crystal material industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated biphenyl or benzyl ether motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal Materials: Acts as a core building block for fluorinated mesogens in the production of advanced display technologies.
• Organic Light-Emitting Diodes (OLEDs): Employed in the synthesis of electron-transport or host materials for optoelectronic devices.
• Cross-Coupling Reactions: The bromomethyl group is a useful handle for further functionalization via Suzuki, Stille, or other palladium-catalyzed cross-coupling reactions.
• Polymer Chemistry: Can be incorporated as a monomer or chain-transfer agent to create specialty polymers with specific fluorinated properties.

Basic Information

Product Name	1-[4-(Bromomethyl)Phenyl]-4-Fluorobenzene
CAS No.	147497-57-2
Molecular Formula	C13H10BrF
Molecular Weight	265.12 g/mol
Synonyms	4'-Fluoro-4-(bromomethyl)biphenyl; 1-Bromomethyl-4-(4-fluorophenyl)benzene; p-(Bromomethyl)-p'-fluorobiphenyl; 4-(Bromomethyl)-4'-fluorobiphenyl; [1,1'-Biphenyl]-4-methanol, 4'-fluoro-, 1-bromo derivative; 4-Fluorophenyl-4-bromomethylbenzene; (4-Fluorophenyl)(4-(bromomethyl)phenyl)methane
EINECS	Contact for details

Quality Control

Our 1-[4-(Bromomethyl)Phenyl]-4-Fluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.