Description

(E)-3-(4-Fluoro-Phenyl)-But-2-Enoic Acid Ethyl Ester is a high-purity fluorinated organic intermediate of significant importance in advanced chemical synthesis. This compound serves as a critical building block for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Building block for developing novel herbicides and fungicides with enhanced efficacy and selectivity.
• Liquid Crystal Materials: Used in the production of fluorinated liquid crystals for advanced display technologies (LCDs).
• Organic Light-Emitting Diodes (OLEDs): Serves as a starting material for electron-transport or host materials in OLED fabrication.
• Chemical Research & Development: Versatile reagent for constructing complex molecular architectures in academic and industrial R&D settings.
• Fine Chemical Production: Intermediate for the manufacture of specialty chemicals, flavors, and fragrances.

Basic Information

Product Name	(E)-3-(4-Fluoro-Phenyl)-But-2-Enoic Acid Ethyl Ester
CAS No.	147471-19-0
Molecular Formula	C₁₂H₁₃FO₂
Molecular Weight	208.23 g/mol
Synonyms	Ethyl (E)-3-(4-Fluorophenyl)but-2-enoate; (E)-Ethyl 3-(4-Fluorophenyl)-2-butenoate; trans-3-(4-Fluorophenyl)-2-butenoic Acid Ethyl Ester; 4-Fluoro-α-methylcinnamic Acid Ethyl Ester; Ethyl (E)-3-(p-Fluorophenyl)crotonate; (E)-3-(p-Fluorophenyl)but-2-enoic Acid Ethyl Ester; 147471-19-0; Ethyl (E)-3-(4-Fluorophenyl)but-2-enoate
EINECS	Contact for details

Quality Control

Our (E)-3-(4-Fluoro-Phenyl)-But-2-Enoic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and isomeric integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee batch-to-batch consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (Area %)
Isomeric Purity ((E)-isomer)	≥ 99.0% (by GC or HPLC)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.