Description

Methanone, (2,3-Dihydro-2-Methyl-5-Benzofuranyl)(2-Fluorophenyl)- is a specialized organic compound featuring a benzofuran core linked to a fluorinated aromatic ketone, representing a valuable synthetic intermediate. This compound matters for its role in facilitating complex molecular construction, particularly in the development of advanced pharmaceutical and agrochemical agents. Industrial researchers and process chemists in fine chemical synthesis need this high-purity building block to enable efficient and scalable routes to target molecules with precision.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Serves as a crucial precursor in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the benzofuran and fluorophenyl motifs.
• Material Science Research: Used in the development of organic semiconductors, liquid crystals, and advanced polymers due to its conjugated molecular structure.
• Chemical Biology Probe Development: Employed as a scaffold for creating molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic projects.

Basic Information

Product Name	Methanone, (2,3-Dihydro-2-Methyl-5-Benzofuranyl)(2-Fluorophenyl)-
CAS No.	147394-58-9
Molecular Formula	C₁₆H₁₃FO₂
Molecular Weight	256.27 g/mol
Synonyms	(2,3-Dihydro-2-methyl-5-benzofuranyl)(2-fluorophenyl)methanone; 2-Fluoro-α-(2-methyl-2,3-dihydrobenzofuran-5-yl)benzyl alcohol (keto form); 5-(2-Fluorobenzoyl)-2-methyl-2,3-dihydrobenzofuran; (2-Fluorophenyl)(2-methyl-2,3-dihydrobenzofuran-5-yl)methanone; 2-Methyl-5-(2-fluorobenzoyl)-2,3-dihydrobenzofuran
EINECS	Contact for details

Quality Control

Our Methanone, (2,3-Dihydro-2-Methyl-5-Benzofuranyl)(2-Fluorophenyl)- is manufactured under strict GMP-like conditions to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Every lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR/LC-MS for structural confirmation. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%; Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.