Description

Ethanone, 1-[4-(Hydroxymethyl)-2,3-Dimethylcyclopentyl]-, [1R-(1Alpha,2Beta,3Beta,4Alpha)]- is a high-purity, stereochemically defined cyclopentyl ketone derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block for the construction of complex molecular architectures, particularly in the pharmaceutical sector. It is essential for research and development chemists and process engineers working on active pharmaceutical ingredients (APIs), fine chemicals, and specialty fragrances.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of prostaglandin analogs and other bioactive molecules.
• Fine Chemical Synthesis: Used as a versatile precursor for constructing complex, stereochemically rich natural product analogs.
• Fragrance & Flavor Ingredient: Serves as a starting material for the development of novel, high-value aroma chemicals with specific olfactory profiles.
• Asymmetric Catalysis Research: Employed as a standard or substrate in the development and testing of new chiral catalysts and synthetic methodologies.
• Agrochemical Research: Potential intermediate in the development of new, targeted crop protection agents with specific stereochemical requirements.
• Material Science: Can be utilized in the synthesis of specialized monomers for advanced polymers.

Basic Information

Product Name	Ethanone, 1-[4-(Hydroxymethyl)-2,3-Dimethylcyclopentyl]-, [1R-(1Alpha,2Beta,3Beta,4Alpha)]-
CAS No.	146683-03-6
Molecular Formula	C10H18O2
Molecular Weight	170.25 g/mol
Synonyms	(1R,2R,3S,4R)-4-(Hydroxymethyl)-2,3-dimethylcyclopentyl methyl ketone; (1R,2R,3S,4R)-2,3-Dimethyl-4-(hydroxymethyl)cyclopentyl methyl ketone; 1-[(1R,2R,3S,4R)-4-(Hydroxymethyl)-2,3-dimethylcyclopentyl]ethanone; 2,3-Dimethyl-4-(hydroxymethyl)cyclopentyl methyl ketone (stereoisomer); A chiral cyclopentyl ketone derivative; Prostaglandin intermediate; Chiral building block CAS 146683-03-6
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high chemical purity. Quality is verified through a comprehensive suite of analytical techniques including HPLC, GC, chiral analysis, and NMR spectroscopy to confirm identity, purity, and stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.