Description

Ethanone, 1-[4-(Hydroxymethyl)-2,3-Dimethylcyclopentyl]-, [1S-(1Alpha,2Beta,3Alpha,4Beta)]- is a high-purity, stereochemically defined cyclopentyl ketone derivative, serving as a critical chiral building block and advanced pharmaceutical intermediate. Its precise stereochemistry and functional groups make it invaluable for synthesizing complex molecules with high enantiomeric purity. This compound is essential for R&D and production in the pharmaceutical and fine chemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, particularly in steroid-like or terpene-based therapeutic agents.
• Asymmetric Synthesis: Used as a chiral precursor or auxiliary in catalytic asymmetric reactions to construct stereogenic centers.
• Fragrance & Flavor Chemistry: Serves as a starting material for the synthesis of high-value aroma chemicals and flavor compounds with specific olfactory profiles.
• Agrochemical Research: Employed in the development of novel, biologically active compounds for crop protection and plant growth regulation.
• Material Science: Investigated as a monomer or functional additive for creating specialized polymers with unique properties.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and medicinal chemistry research.

Basic Information

Item	Details
Product Name	Ethanone, 1-[4-(Hydroxymethyl)-2,3-Dimethylcyclopentyl]-, [1S-(1Alpha,2Beta,3Alpha,4Beta)]-
CAS No.	146683-02-5
Molecular Formula	C10H18O2
Molecular Weight	170.25 g/mol
Synonyms	(1S,2R,3R,4R)-4-(Hydroxymethyl)-2,3-dimethylcyclopentyl methyl ketone; (1S,2R,3R,4R)-2,3-Dimethyl-4-(hydroxymethyl)cyclopentyl methyl ketone; 1-[(1S,2R,3R,4R)-4-(Hydroxymethyl)-2,3-dimethylcyclopentyl]ethanone; [1S-(1α,2β,3α,4β)]-1-[4-(Hydroxymethyl)-2,3-dimethylcyclopentyl]ethanone; Chiral Cyclopentyl Ketone Derivative; CAS 146683-02-5
EINECS	Contact for details

Quality Control

Our Ethanone, 1-[4-(Hydroxymethyl)-2,3-Dimethylcyclopentyl]-, [1S-(1Alpha,2Beta,3Alpha,4Beta)]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with high-purity pharmaceutical intermediate standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.