Description

2-(4-Cyanophenyl)-3'-Iodoacetophenone is a high-value, multi-functional organic intermediate characterized by its distinct aromatic ketone structure with cyano and iodo substituents. This compound is critical for advanced organic synthesis, offering versatile reactivity for constructing complex molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly in medicinal chemistry research for creating libraries of bioactive molecules.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its halogen and nitrile groups enable specific modes of action.
• Ligand and Catalyst Precursor: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the creation of organic electronic materials and liquid crystals due to its rigid, conjugated backbone.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects requiring precise functionalization of aromatic systems.
• Academic and R&D Laboratories: Utilized in fundamental organic chemistry research to explore new reaction pathways and synthetic methodologies.

Basic Information

Product Name	2-(4-Cyanophenyl)-3'-Iodoacetophenone
CAS No.	146653-53-4
Molecular Formula	C15H10INO
Molecular Weight	347.15 g/mol
Synonyms	3'-Iodo-2-(4-cyanophenyl)acetophenone; 1-[3-Iodophenyl]-2-(4-cyanophenyl)ethanone; 2-(4-Cyanophenyl)-1-(3-iodophenyl)ethan-1-one; 3-Iododesoxybenzoin-4'-carbonitrile; (3-Iodophenyl)(4-cyanophenyl)methanone (tautomeric form); α-(4-Cyanophenyl)-3-iodoacetophenone
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Cyanophenyl)-3'-Iodoacetophenone is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, which include data from HPLC, NMR, and IR spectroscopy. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.