Description

1-(2-Hydroxy-5-Trifluoromethoxy-Phenyl)-Ethanone is a specialized aromatic ketone featuring both a phenolic hydroxyl group and a trifluoromethoxy substituent, making it a valuable fluorinated building block. This unique structure provides enhanced lipophilicity and metabolic stability, which is critical for developing advanced chemical intermediates. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key fluorinated synthon for the research and development of new drug candidates, particularly in areas requiring improved bioavailability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethoxy group can enhance biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals that benefit from fluorine's unique electronic properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, etherifications, and other transformations to introduce complex aromatic motifs.

Basic Information

Product Name	1-(2-Hydroxy-5-Trifluoromethoxy-Phenyl)-Ethanone
CAS No.	146575-64-6
Molecular Formula	C9H7F3O3
Molecular Weight	220.15 g/mol
Synonyms	2'-Hydroxy-5'-(trifluoromethoxy)acetophenone; 1-[2-Hydroxy-5-(trifluoromethoxy)phenyl]ethanone; 2-Acetyl-4-(trifluoromethoxy)phenol; 5-Trifluoromethoxy-2-hydroxyacetophenone; 2-Hydroxy-5-trifluoromethoxyacetophenone; α-Acetyl-5-(trifluoromethoxy)salicyl alcohol (tautomer); 1-(2-Hydroxy-5-trifluoromethoxyphenyl)ethan-1-one
EINECS	Contact for details

Quality Control

Our 1-(2-Hydroxy-5-Trifluoromethoxy-Phenyl)-Ethanone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting key parameters such as assay and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.