Description

1,3-Dioxolane-4,5-Dicarboxaldehyde, 2,2-Dimethyl-, cis- (9Ci) is a specialized, high-purity dialdehyde derivative of a protected glyoxal, serving as a versatile and reactive bifunctional building block in advanced organic synthesis. Its core value lies in providing a chemically defined, symmetrical platform for constructing complex heterocyclic and macrocyclic structures under controlled conditions. This compound is essential for researchers and process chemists in pharmaceutical development, agrochemical discovery, and materials science who require precise, multi-functional intermediates for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly for constructing fused heterocycles and chiral ligands.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, where its dialdehyde functionality enables the creation of specific bioactive ring systems.
• Polymer & Material Science: Acts as a cross-linking agent or monomer for producing specialty polymers, resins, and dendrimers with tailored properties.
• Chemical Research & Development: A valuable reagent for methodological studies in organic chemistry, including cycloaddition reactions and the development of new catalytic processes.
• Ligand & Catalyst Preparation: Serves as a backbone for synthesizing sophisticated chelating ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	1,3-Dioxolane-4,5-Dicarboxaldehyde, 2,2-Dimethyl-, cis- (9Ci)
CAS No.	146566-82-7
Molecular Formula	C8H12O5
Molecular Weight	188.18 g/mol
Synonyms	2,2-Dimethyl-1,3-dioxolane-4,5-dicarboxaldehyde, cis-; (4R,5R)-2,2-Dimethyl-1,3-dioxolane-4,5-dicarboxaldehyde; (4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-dicarboxaldehyde; cis-2,2-Dimethyl-1,3-dioxolane-4,5-dicarbaldehyde; 1,3-Dioxolane-4,5-dicarboxaldehyde, 2,2-dimethyl-, (4R,5R)-rel-; Protected Glyoxal Derivative
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane-4,5-Dicarboxaldehyde, 2,2-Dimethyl-, cis- (9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC to confirm identity, purity, and isomeric composition. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity (cis-)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.