Description

2-(4-Fluoro-Benzoyl)-3-Oxo-Butyric Acid Ethyl Ester is a high-purity organic intermediate characterized by its β-keto ester and fluorinated benzoyl functional groups. This compound is valued for its role as a versatile building block in the synthesis of complex molecules, particularly in the pharmaceutical sector. It is primarily sought after by research institutions and manufacturers engaged in developing active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, especially those containing fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where the fluorine moiety enhances biological activity.
• Material Science Research: Serves as a monomer or building block for specialty polymers and advanced organic materials.
• Chemical Research & Development: Employed in organic synthesis for constructing complex molecular architectures via Claisen condensation and related reactions.
• Fluorine Chemistry Studies: A valuable compound for investigating the effects of fluorine substitution on chemical reactivity and physical properties.

Basic Information

Product Name	2-(4-Fluoro-Benzoyl)-3-Oxo-Butyric Acid Ethyl Ester
CAS No.	146198-68-7
Molecular Formula	C13H13FO4
Molecular Weight	252.24 g/mol
Synonyms	Ethyl 2-(4-Fluorobenzoyl)-3-oxobutanoate; Ethyl 4-Fluorobenzoylacetate; 3-Oxo-2-(4-fluorobenzoyl)butyric Acid Ethyl Ester; 2-(p-Fluorobenzoyl)acetoacetic Acid Ethyl Ester; 4-Fluorobenzoylacetic Acid Ethyl Ester; Ethyl (4-Fluorobenzoyl)acetate; 146198-68-7; Ethyl 4-fluorobenzoylacetate
EINECS	Contact for details

Quality Control

Our 2-(4-Fluoro-Benzoyl)-3-Oxo-Butyric Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.