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1-(2-Fluorophenyl)-2,5-Dimethylpyrrole CAS NO 146135-20-8


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CAS No.:146135-20-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-(2-Fluorophenyl)-2,5-Dimethylpyrrole is a high-purity fluorinated pyrrole derivative, a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring a fluorinated aromatic ring fused to a substituted pyrrole core, makes it a critical intermediate for developing novel compounds with tailored properties. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and materials science industries seeking to incorporate fluorinated heterocyclic motifs into their target molecules.

Application

  • Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
  • Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity, metabolic stability, and lipophilicity.
  • Organic Electronic Materials: Acts as a precursor for constructing conjugated molecules and polymers for applications in organic light-emitting diodes (OLEDs), field-effect transistors (OFETs), and photovoltaic cells.
  • Ligand and Catalyst Development: Employed in the preparation of specialized nitrogen-containing ligands for transition metal catalysis, facilitating asymmetric synthesis and cross-coupling reactions.
  • Fluorine Chemistry Research: A valuable substrate for studying structure-activity relationships (SAR) and the effects of fluorine substitution on the physicochemical properties of heterocyclic compounds.
  • Dye and Pigment Synthesis: Utilized as a building block for creating novel fluorinated dyes and pigments with specific color, stability, and solubility characteristics.

Basic Information

Product Name 1-(2-Fluorophenyl)-2,5-Dimethylpyrrole
CAS No. 146135-20-8
Molecular Formula C12H12FN
Molecular Weight 189.23 g/mol
Synonyms 2,5-Dimethyl-1-(2-fluorophenyl)-1H-pyrrole; 1-(2-Fluorophenyl)-2,5-dimethyl-1H-pyrrole; 2-Fluoro-N-(2,5-dimethyl-1H-pyrrol-1-yl)benzene; 1H-Pyrrole, 1-(2-fluorophenyl)-2,5-dimethyl-; 2,5-Dimethyl-1-(o-fluorophenyl)pyrrole; 1-(o-Fluorophenyl)-2,5-dimethylpyrrole; 2-Fluorophenyl-2,5-dimethylpyrrole
EINECS Contact for details

Quality Control

Our 1-(2-Fluorophenyl)-2,5-Dimethylpyrrole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming the product meets the agreed specifications for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder or solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0% (Area %)
Melting Point Contact for details
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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