Description

(Piperidin-4-Yloxy)-Acetic Acid is a versatile and high-purity organic building block with significant utility in advanced chemical synthesis. Its molecular structure, featuring both a piperidine ring and a carboxylic acid functional group, makes it a critical intermediate for constructing complex pharmacologically active molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and plant growth regulators requiring specific chiral or structural motifs.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal complexation.
• Bioconjugation and Linker Chemistry: The carboxylic acid group enables its use as a spacer or linker molecule in bioconjugation for antibody-drug conjugates (ADCs) or probe development.
• Custom Synthesis and R&D: Employed by contract research organizations (CROs) and custom synthesis facilities for client-specific molecule construction.
• Academic Research: A valuable reagent for universities and research institutes studying medicinal chemistry, organic synthesis methodologies, and chemical biology.

Basic Information

Product Name	(Piperidin-4-Yloxy)-Acetic Acid
CAS No.	146117-93-3
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	4-(Carboxymethoxy)piperidine; 4-Piperidinol, 1-(carboxymethyl)-; 1-(Carboxymethyl)-4-piperidinol; Acetic acid, (4-piperidinyloxy)-; (4-Piperidyloxy)acetic acid; 4-Hydroxypiperidine-1-acetic acid; (Piperidin-4-yloxy)acetic acid
EINECS	Contact for details

Quality Control

Every batch of (Piperidin-4-Yloxy)-Acetic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.