Description

Cyclopropanecarboxylic Acid, 2-(1,2-Dihydroxyethyl)-, Methyl Ester, [1Alpha,2Beta(S*)]- is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its unique cyclopropane ring fused with a dihydroxyethyl side chain makes it a valuable precursor for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including potential antiviral, anticancer, or central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the stereochemistry of the molecule is critical for biological activity and selectivity.
• Asymmetric Catalysis Research: Serves as a sophisticated ligand precursor or a test substrate in the development of new chiral catalysts and synthetic methodologies.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & Institutional Research: A valuable compound for studies in synthetic organic chemistry, medicinal chemistry, and material science at universities and R&D institutes.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-(1,2-Dihydroxyethyl)-, Methyl Ester, [1Alpha,2Beta(S*)]-
CAS No.	146061-88-3
Molecular Formula	C8H14O5
Molecular Weight	190.19 g/mol
Synonyms	(1S,2R)-2-(1,2-Dihydroxyethyl)cyclopropanecarboxylic acid methyl ester; Methyl (1S,2R)-2-(1,2-dihydroxyethyl)cyclopropanecarboxylate; [1α,2β(S*)]-2-(1,2-Dihydroxyethyl)cyclopropanecarboxylic Acid Methyl Ester; (1S,2R)-rel-2-(1,2-Dihydroxyethyl)cyclopropanecarboxylic Acid Methyl Ester; Cyclopropanecarboxylic acid, 2-(1,2-dihydroxyethyl)-, methyl ester, (1S,2R)-rel-; Chiral cyclopropane diol ester; Methyl 2-(1,2-dihydroxyethyl)cyclopropanecarboxylate
EINECS	Contact for details

Quality Control

Our production of this advanced chiral intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and high stereochemical purity. Each lot is characterized using advanced analytical techniques including Chiral HPLC, NMR, and Mass Spectrometry to confirm identity, enantiomeric excess (ee), and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.