Description

4-Trifluoromethylphenylmethylsulfone is a high-purity organosulfur compound featuring a trifluoromethylphenyl group, making it a valuable synthetic intermediate. This compound is prized for its role in facilitating the introduction of the sulfone and trifluoromethylphenyl functionalities into target molecules, which are critical for modulating physicochemical properties. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of active ingredients and advanced materials.

Application

• Key pharmaceutical intermediate in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Building block for agrochemical active ingredients, such as herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Precursor in material science for creating specialty polymers and liquid crystals with unique electronic and thermal properties.
• Versatile reagent in organic synthesis for Suzuki-Miyaura and other cross-coupling reactions to construct complex biaryl systems.
• Intermediate for dye and pigment chemistry, contributing to the development of high-performance coloring agents.

Basic Information

Item	Details
Product Name	4-Trifluoromethylphenylmethylsulfone
CAS No.	145963-48-0
Molecular Formula	C8H7F3O2S
Molecular Weight	224.20 g/mol
Synonyms	1-Methylsulfonyl-4-(trifluoromethyl)benzene; (4-(Trifluoromethyl)phenyl)(methyl)sulfone; p-(Trifluoromethyl)phenyl Methyl Sulfone; 4-(Methylsulfonyl)benzotrifluoride; α,α,α-Trifluoro-4-(methylsulfonyl)toluene; 4-Trifluoromethyl Phenyl Methyl Sulfone
EINECS	Contact for details

Quality Control

Every batch of 4-Trifluoromethylphenylmethylsulfone is manufactured under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support customer audits and regulatory documentation as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.