Description

Cyclopentanecarboxaldehyde, 1,4-Dimethyl-2-Oxo-, trans- (9Ci) is a specialized chiral aldehyde building block of significant interest in advanced organic synthesis. Its unique structural motif, featuring both a reactive aldehyde group and a ketone within a constrained cyclopentane ring, makes it a valuable precursor for constructing complex, stereodefined molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly those requiring stereochemical control.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides where specific stereochemistry impacts biological activity.
• Asymmetric Catalysis Research: Serves as a model substrate or a chiral ligand precursor in the development of new catalytic methodologies.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring the trans-1,4-dimethyl-2-oxo-cyclopentane scaffold.
• Academic & R&D Laboratories: A valuable tool for methodological studies in organic chemistry and for the preparation of libraries of compounds for biological screening.

Basic Information

Product Name	Cyclopentanecarboxaldehyde, 1,4-Dimethyl-2-Oxo-, trans- (9Ci)
CAS No.	145948-65-8
Molecular Formula	C8H12O2
Molecular Weight	140.18 g/mol
Synonyms	trans-1,4-Dimethyl-2-oxocyclopentanecarboxaldehyde; (1R,4S)-1,4-Dimethyl-2-oxocyclopentanecarbaldehyde; (1S,4R)-1,4-Dimethyl-2-oxocyclopentanecarbaldehyde; 2-Oxo-1,4-dimethylcyclopentanecarboxaldehyde, trans-; 1,4-Dimethyl-2-oxocyclopentanecarbaldehyde; trans-2-Oxo-1,4-dimethylcyclopentanecarboxaldehyde
EINECS	Contact for details

Quality Control

Our Cyclopentanecarboxaldehyde, 1,4-Dimethyl-2-Oxo-, trans- (9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as chiral purity, chemical purity, and identity confirmation. Our quality systems are designed to support cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Allow the container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (trans isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.