Description

29-Methylidene-2,3-Oxidosqualene is a key oxidosqualene derivative, a crucial biosynthetic intermediate in the production of triterpenoids and sterols. This compound matters as a vital research chemical and a potential precursor for developing novel pharmaceutical agents targeting cholesterol biosynthesis and other metabolic pathways. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on enzymology, metabolic studies, and the synthesis of bioactive natural products.

Application

• Biochemical Research: Used as a critical substrate for studying the enzyme 2,3-oxidosqualene cyclase and related cyclization mechanisms in sterol biosynthesis.
• Pharmaceutical Development: Serves as a key intermediate in the research and synthesis of novel cholesterol-lowering agents and other therapeutic triterpenoids.
• Enzymology Studies: Employed in in vitro assays to investigate enzyme kinetics, inhibition, and the catalytic pathways of squalene epoxidase and cyclase enzymes.
• Metabolic Pathway Analysis: Utilized as a tracer or standard in metabolic flux studies to understand the biosynthesis of steroids and hopanoids.
• Fine Chemical Synthesis: Acts as a specialized building block for the synthetic organic chemistry of complex polycyclic natural products.
• Academic Research: Fundamental tool in university laboratories for teaching and research in advanced organic chemistry and bioorganic chemistry.

Basic Information

Product Name	29-Methylidene-2,3-Oxidosqualene
CAS No.	145919-42-2
Molecular Formula	C31H50O
Molecular Weight	438.73 g/mol
Synonyms	(3S)-2,3-Epoxy-2,3-dihydrosqualene; 29-Methylenesqualene-2,3-epoxide; 2,3-Oxidosqualene, 29-methylene-; (S)-2,3-Epoxy-29-methylenesqualene; 29-Methylidene-2,3-oxidosqualene; 2,3-Epoxy-29-methylidenesqualene; 29-Methylenesqualene 2,3-epoxide
EINECS	Contact for details

Quality Control

Our 29-Methylidene-2,3-Oxidosqualene is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is characterized and tested using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to minimize oxidation. Keep the container in a cool, dry, and well-ventilated area, away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Solubility	Soluble in common organic solvents (e.g., DCM, chloroform, THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.