Description

2-Pentanone, 5-(3-Methyl-3H-Diazirin-3-Yl)- (9Ci) is a specialized diazirine-functionalized ketone, a high-value building block in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise photoaffinity labeling and cross-linking agents for probing biomolecular interactions. It is primarily utilized in pharmaceutical R&D, agrochemical discovery, and materials science for developing novel probes and functional polymers. The product, identified by CAS No. 145838-81-9, is supplied to meet the stringent demands of these innovative fields.

Application

• Photoaffinity Labeling Probes: A key precursor for synthesizing photoactivatable cross-linkers used in chemical biology and proteomics to study protein-ligand interactions.
• Pharmaceutical Research: Employed in the discovery and development of new drug candidates, particularly for creating targeted covalent inhibitors.
• Agrochemical Development: Used in the synthesis of novel active ingredients and study of their mode of action in plant systems.
• Polymer & Materials Science: Serves as a functional monomer or cross-linking agent for creating light-responsive polymers and smart materials.
• Bioconjugation Chemistry: Facilitates the stable attachment of reporter molecules (e.g., fluorophores, biotin) to biomolecules under controlled light activation.
• Academic & Industrial R&D: Essential for fundamental research in organic chemistry, biochemistry, and medicinal chemistry laboratories worldwide.

Basic Information

Product Name	2-Pentanone, 5-(3-Methyl-3H-Diazirin-3-Yl)- (9Ci)
CAS No.	145838-81-9
Molecular Formula	C7H12N2O
Molecular Weight	140.18 g/mol
Synonyms	5-(3-Methyl-3H-diazirin-3-yl)pentan-2-one; 3-Methyl-3-(4-oxopentyl)-3H-diazirine; 3H-Diazirine, 3-methyl-3-(4-oxopentyl)-; Diazirine-functionalized ketone; Photoaffinity labeling ketone; 4-Oxo-1-(3-methyl-3H-diazirin-3-yl)pentane; 3-(4-Oxopentyl)-3-methyl-3H-diazirine
EINECS	Contact for details

Quality Control

Our 2-Pentanone, 5-(3-Methyl-3H-Diazirin-3-Yl)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance for sensitive research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and highly volatile nature, minimize exposure to light and air during handling. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.