Description

4-Oxoazetidine-2-Carbaldehyde is a high-value, versatile β-lactam derivative and a crucial advanced pharmaceutical intermediate. This compound serves as a key synthon in the synthesis of novel β-lactam antibiotics and other biologically active molecules, enabling the development of next-generation therapeutics. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel monocyclic β-lactam antibiotics and protease inhibitors.
• Organic Synthesis: Serves as a versatile precursor for the construction of complex heterocyclic compounds and chiral molecules.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new drug candidates.
• Agrochemical Development: Employed in the research and synthesis of new active ingredients with potential herbicidal or fungicidal properties.
• Bioconjugation Chemistry: The aldehyde functional group allows for site-specific modification of proteins and other biomolecules.
• Academic & Industrial R&D: Fundamental research reagent for exploring new chemical reactions and methodologies involving strained ring systems.

Basic Information

Product Name	4-Oxoazetidine-2-Carbaldehyde
CAS No.	145802-97-7
Molecular Formula	C4H5NO2
Molecular Weight	99.09 g/mol
Synonyms	2-Formylazetidin-4-one; (4-Oxoazetidin-2-yl)methanal; 2-Azetidinecarboxaldehyde, 4-oxo-; 4-Oxo-2-azetidinecarboxaldehyde; Azetidine-2-carbaldehyde, 4-oxo-; β-Lactam-2-carboxaldehyde, 4-oxo-; 4-Oxoazetidine-2-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 4-Oxoazetidine-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.