Description

3,4-Difluorobenzenesulfonyl Chloride is a high-purity, reactive organosulfur intermediate essential for advanced chemical synthesis. Its value lies in its dual functionality as a sulfonylating agent and the presence of fluorine atoms, which are critical for modulating the physicochemical properties of target molecules. This compound is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Research: A versatile reagent in organic synthesis for introducing the 3,4-difluorobenzenesulfonyl moiety into complex molecular architectures.
• Dye and Pigment Manufacturing: Intermediate for creating sulfonated fluorinated dyes with improved color fastness and solubility properties.

Basic Information

Product Name	3,4-Difluorobenzenesulfonyl Chloride
CAS No.	145758-05-0
Molecular Formula	C6H3ClF2O2S
Molecular Weight	212.60 g/mol
Synonyms	3,4-Difluorobenzene-1-sulfonyl chloride; 1,2-Difluoro-4-(chlorosulfonyl)benzene; 3,4-Difluorophenylsulfonyl chloride; Benzenesulfonyl chloride, 3,4-difluoro-; 3,4-DFBS-Cl
EINECS	Contact for details

Quality Control

Every batch of our 3,4-Difluorobenzenesulfonyl Chloride is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after initial opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.