Description

2-Fluoro-2-Methylpropyl Trifluoromethanesulfonate is a specialized fluorinated sulfonate ester, a high-value building block in advanced organic synthesis. Its core value lies in its exceptional reactivity as an alkylating and triflating agent, enabling the efficient introduction of the 2-fluoro-2-methylpropyl group into complex molecular architectures. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key reagent for the synthesis of fluorinated active pharmaceutical ingredients (APIs), leveraging the fluorine atom to modulate metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating novel fluorinated pesticides and herbicides, where the fluorine substituent enhances biological activity and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized fluorinated ligands and organometallic catalysts used in asymmetric synthesis.
• Polymer & Material Science: Employed to introduce fluorinated side chains into polymers, imparting unique properties like oil/water repellency, chemical resistance, and low surface energy.
• Fluorine Chemistry Research: A vital tool in academic and industrial R&D for exploring new C-F bond formation strategies and developing fluorination methodologies.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex, high-value fluorinated fine chemicals and specialty compounds.

Basic Information

Product Name	2-Fluoro-2-Methylpropyl Trifluoromethanesulfonate
CAS No.	145349-17-3
Molecular Formula	C5H8F4O3S
Molecular Weight	224.17 g/mol
Synonyms	2-Fluoro-2-methylpropyl triflate; (2-Fluoro-2-methylpropyl) trifluoromethanesulfonate; 1,1,1-Trifluoro-N-[(2-fluoro-2-methylpropyl)oxy]methanesulfonamide; Trifluoromethanesulfonic acid 2-fluoro-2-methylpropyl ester; 2-Fluoro-2-methyl-1-propyl triflate; 2-Fluoro-tert-butyl triflate; 2-Fluoro-2-methylpropyl trifluoromethanesulphonate
EINECS	Contact for details

Quality Control

Our 2-Fluoro-2-Methylpropyl Trifluoromethanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at recommended temperatures between 2°C and 8°C. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
NMR Purity	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.