Description

1-(4-(Difluoromethylthio)Phenyl)Ethanone is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity imparted by the difluoromethylthio (-SCF2H) group, which serves as a versatile precursor for introducing fluorinated motifs into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and liquid crystals with unique electronic properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and as a substrate for introducing the difluoromethylthioether group into complex organic frameworks.
• Fluorine Chemistry Studies: A valuable reference compound for academic and industrial research into the behavior and applications of organofluorine chemistry.

Basic Information

Product Name	1-(4-(Difluoromethylthio)Phenyl)Ethanone
CAS No.	145326-60-9
Molecular Formula	C9H8F2OS
Molecular Weight	202.22 g/mol
Synonyms	4'-(Difluoromethylthio)acetophenone; 1-[4-(Difluoromethylsulfanyl)phenyl]ethanone; p-(Difluoromethylthio)acetophenone; 4-Acetylphenyl difluoromethyl sulfide; Acetophenone, 4'-(difluoromethylthio)-; Ethanone, 1-[4-(difluoromethylthio)phenyl]-
EINECS	Contact for details

Quality Control

Our 1-(4-(Difluoromethylthio)Phenyl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.