Description

Cyclopropanecarboxylic Acid, 2-Ethoxy-3-Methyl-, 1,1-Dimethylethyl Ester, (1Alpha,2Alpha,3Ba)- (9Ci) is a high-purity, stereochemically defined cyclopropane derivative, serving as a critical chiral building block in advanced organic synthesis. Its precise stereochemistry and functional groups make it an invaluable intermediate for constructing complex molecular architectures with high enantiomeric purity. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used in the production of advanced, stereoselective pesticides and herbicides where specific spatial orientation is crucial for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and liquid crystals that require rigid, cyclopropane-based structural units.
• Academic & Process Chemistry: A valuable compound for methodological studies in stereoselective synthesis and scale-up process optimization in university and industrial R&D labs.

Basic Information

Item	Details
Product Name	Cyclopropanecarboxylic Acid, 2-Ethoxy-3-Methyl-, 1,1-Dimethylethyl Ester, (1Alpha,2Alpha,3Ba)- (9Ci)
CAS No.	145164-86-9
Molecular Formula	C12H22O3
Molecular Weight	214.30 g/mol
Synonyms	(1α,2α,3β)-2-Ethoxy-3-methylcyclopropanecarboxylic acid tert-butyl ester; tert-Butyl (1α,2α,3β)-2-ethoxy-3-methylcyclopropanecarboxylate; (1R,2R,3S)-2-Ethoxy-3-methylcyclopropanecarboxylic acid 1,1-dimethylethyl ester; 1,1-Dimethylethyl (1α,2α,3β)-2-ethoxy-3-methyl-1-cyclopropanecarboxylate; (1Alpha,2Alpha,3Beta)-2-Ethoxy-3-methylcyclopropanecarboxylic acid tert-butyl ester; tert-Butyl trans-2-ethoxy-3-methylcyclopropanecarboxylate (stereospecific); Chiral cyclopropane ester intermediate
EINECS	Contact for details

Quality Control

Our production of Cyclopropanecarboxylic Acid, 2-Ethoxy-3-Methyl-, 1,1-Dimethylethyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric excess (ee). Quality is verified through advanced analytical techniques including chiral HPLC, GC, and NMR spectroscopy. Certificates of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles are provided with every shipment, supporting compliance in cGMP and ISO 9001 environments for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere to maximize shelf-life stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.