Description

1-Bromo-4-(1-fluorovinyl)benzene is a versatile halogenated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a bromine substituent and a reactive fluorovinyl group, makes it a critical precursor for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions and fluorinated scaffold development.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of active pharmaceutical ingredients (APIs), particularly for introducing fluorinated aromatic moieties.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where fluorinated compounds enhance biological activity and stability.
• Material Science Precursor: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials that require specific halogenated aromatic units.
• Cross-Coupling Reactions: Acts as an electrophilic partner in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Fluorine Chemistry Research: A valuable substrate for studying and developing new methodologies in fluorovinyl chemistry and C-F bond transformations.
• Ligand and Catalyst Development: Utilized to create novel phosphine or N-heterocyclic carbene ligands with fluorinated backbones for catalysis.

Basic Information

Item	Details
Product Name	1-Bromo-4-(1-fluorovinyl)benzene
CAS No.	144989-16-2
Molecular Formula	C8H6BrF
Molecular Weight	201.04 g/mol
Synonyms	4-Bromo-α-fluorostyrene; 1-Bromo-4-(fluorovinyl)benzene; p-Bromo-α-fluorostyrene; (1-Fluorovinyl)-4-bromobenzene; 4-Bromo-(1-fluorovinyl)benzene; 4-Bromostyrene, α-fluoro-; 144989-16-2; Benzene, 1-bromo-4-(1-fluorovinyl)-
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-(1-fluorovinyl)benzene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture ingress and potential decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.