Description

2-Amino-2,3-dihydro-1H-indene-2-carbonitrile is a versatile bicyclic nitrile building block of significant interest in advanced organic synthesis. Its unique fused ring structure containing both amino and nitrile functional groups makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and metabolic conditions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its bicyclic scaffold for enhanced biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multistep synthesis of complex dyes, pigments, and advanced materials requiring a rigid, functionalized indane core.
• Academic and Contract Research: Utilized in university and CRO laboratories for methodological studies in organic chemistry and the exploration of new chemical spaces.

Basic Information

Product Name	2-Amino-2,3-dihydro-1H-indene-2-carbonitrile
CAS No.	144800-68-0
Molecular Formula	C10H10N2
Molecular Weight	158.20 g/mol
Synonyms	2-Aminoindane-2-carbonitrile; 2-Cyano-2,3-dihydro-1H-inden-2-amine; 2-Amino-2-cyanoindane; 2-Aminoindan-2-carbonitrile; 1H-Indene-2-carbonitrile, 2-amino-2,3-dihydro-; 2-Amino-2,3-dihydro-1H-indene-2-carbonitrile; 2-Amino-2-cyano-2,3-dihydro-1H-indene
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-2,3-dihydro-1H-indene-2-carbonitrile is produced under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and acids. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.