Description

Fmoc-Dl-Tryptophan CAS NO 144701-22-4 is a protected amino acid derivative where the tryptophan side chain and amine group are shielded by the fluorenylmethyloxycarbonyl (Fmoc) protecting group. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled and sequential assembly of complex peptides. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers involved in developing therapeutic peptides, biochemical probes, and novel materials.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental Fmoc-protected amino acid for the automated or manual synthesis of custom peptides.
• Pharmaceutical Research: Used in the discovery and development of peptide-based drugs, hormones, and enzyme inhibitors.
• Bioconjugation: Serves as a precursor for creating peptide tags or fluorescent probes for protein labeling and tracking.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to identify bioactive compounds.
• Academic & Biochemical Studies: Essential for studying protein structure-function relationships, enzyme kinetics, and receptor-ligand interactions.
• Material Science: A component in synthesizing peptide-polymer hybrids or biomimetic materials.

Basic Information

Product Name	Fmoc-Dl-Tryptophan
CAS No.	144701-22-4
Molecular Formula	C26H22N2O4
Molecular Weight	426.47 g/mol
Synonyms	N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-DL-tryptophan; Fmoc-DL-Trp-OH; Fmoc-Tryptophan; N-Fmoc-DL-tryptophan; (RS)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-(1H-indol-3-yl)propanoic acid; DL-Fmoc-Tryptophan; 2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1H-indol-3-yl)propanoic acid
EINECS	Contact for details

Quality Control

Our Fmoc-Dl-Tryptophan is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.