Description

1-Propanone, 2,2-Difluoro-1-(4-Methoxyphenyl)- (9Ci) is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity imparted by the difluoroacetone moiety adjacent to an aromatic ring, enabling precise molecular construction. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides that require fluorinated motifs for enhanced activity and stability.
• Liquid Crystal & OLED Material Research: Serves as a precursor in the synthesis of fluorinated organic electronic materials for displays and lighting.
• Advanced Polymer Chemistry: Employed as a monomer or cross-linking agent to introduce fluorine atoms into polymer backbones, modifying thermal and chemical resistance.
• Organic Synthesis Building Block: Utilized in various name reactions (e.g., Friedel-Crafts, Grignard additions) to introduce the 2,2-difluoro-1-aryl-1-propanone functional group.
• Chemical Research & Development: Essential for academic and industrial R&D exploring new fluorination methodologies and the properties of fluorine-containing compounds.

Basic Information

Product Name	1-Propanone, 2,2-Difluoro-1-(4-Methoxyphenyl)- (9Ci)
CAS No.	144464-70-0
Molecular Formula	C10H10F2O2
Molecular Weight	200.18 g/mol
Synonyms	2,2-Difluoro-1-(4-methoxyphenyl)propan-1-one; 4-Methoxy-2,2-difluoropropiophenone; 1-(4-Methoxyphenyl)-2,2-difluoropropan-1-one; p-Methoxy-α,α-difluoropropiophenone; DFMP; Difluoro(4-methoxyphenyl)acetone; 4'-Methoxy-2,2-difluoropropiophenone
EINECS	Contact for details

Quality Control

Our 1-Propanone, 2,2-Difluoro-1-(4-Methoxyphenyl)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with ISO standards and meets the stringent requirements of R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.