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4-Biphenylboronic Acid, Pinacol Ester CAS NO 144432-80-4


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CAS No.:144432-80-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Biphenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative, a crucial intermediate in modern synthetic chemistry. Its primary value lies in its enhanced stability compared to the free boronic acid, making it an essential reagent for reliable Suzuki-Miyaura cross-coupling reactions. This compound is in high demand for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to construct complex biaryl frameworks.

Application

  • Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
  • Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides requiring specific biphenyl structures.
  • Liquid Crystal & OLED Materials: Serves as a precursor for creating organic electronic materials and liquid crystal display (LCD) components.
  • Polymer Chemistry: Enables the incorporation of biphenyl units into specialty polymers and advanced resins.
  • Chemical Research & Development: A versatile reagent for academic and industrial R&D in organic synthesis and methodology development.
  • Material Science: Used in the synthesis of metal-organic frameworks (MOFs) and other functional materials.

Basic Information

Product Name 4-Biphenylboronic Acid, Pinacol Ester
CAS No. 144432-80-4
Molecular Formula C18H21BO2
Molecular Weight 280.17 g/mol
Synonyms 4-Biphenylboronic Acid Pinacol Ester; [1,1'-Biphenyl]-4-boronic Acid, Pinacol Ester; 4-(Pinacolboryl)biphenyl; 4-Biphenylboronic Acid Pinanediol Ester (common alternative); 4-Biphenylboronate Pinacol Ester; 4-Bpin-Biphenyl; (4-Biphenylyl)boronic Acid Pinacol Ester; p-Biphenylboronic Acid Pinacol Ester
EINECS Contact for details

Quality Control

Our 4-Biphenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Melting Point Contact for details
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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