Description

4,7-Methano-1H-Indene,1-Fluoro-3A,4,7,7A-Tetrahydro-(9Ci) is a specialized fluorinated bicyclic organic compound with the CAS registry number 144427-16-7. This high-value intermediate is critical for advanced organic synthesis, particularly in the development of novel pharmaceuticals and agrochemicals where the introduction of fluorine atoms is required to modulate biological activity and metabolic stability. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of fluorinated active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and anti-inflammatory drugs.
• Agrochemical Synthesis: Used in the research and production of advanced fluorinated pesticides and herbicides, where fluorine enhances lipophilicity and target binding.
• Material Science Research: Acts as a precursor for developing novel fluorinated polymers or liquid crystals with unique thermal and optical properties.
• Organic Synthesis & Catalysis: Employed in academic and industrial research for studying fluorination reactions and developing new catalytic methodologies.
• Fine Chemical Production: Utilized in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.

Basic Information

Product Name	4,7-Methano-1H-Indene,1-Fluoro-3A,4,7,7A-Tetrahydro-(9Ci)
CAS No.	144427-16-7
Molecular Formula	C10H11F
Molecular Weight	150.19 g/mol
Synonyms	1-Fluoro-3a,4,7,7a-tetrahydro-4,7-methano-1H-indene; 1-Fluoro-3a,4,7,7a-tetrahydro-4,7-methanoindene; 1-Fluorotetrahydro-4,7-methanoindene; NSC 339063; 4,7-Methano-1H-indene, 1-fluoro-3a,4,7,7a-tetrahydro-; Fluorinated norbornene derivative
EINECS	Contact for details

Quality Control

Our 4,7-Methano-1H-Indene,1-Fluoro-3A,4,7,7A-Tetrahydro-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/GC-MS for structural confirmation, to ensure it meets the stringent requirements for research and process chemistry. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.