Description

1,3-Dioxane-2-Carboxaldehyde, 2,4-Dimethyl-, (2S-Cis)- (9Ci) is a specialized chiral aldehyde derivative of 1,3-dioxane, serving as a high-value synthetic building block. This compound matters for its role in facilitating stereoselective organic synthesis, enabling the construction of complex molecules with precise spatial orientation. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of chiral ligands used in asymmetric hydrogenation and other catalytic processes.
• Fine Chemical Building Block: Employed in academic and industrial research labs for the construction of complex natural product analogs and specialty chemicals.
• Material Science Research: Potential monomer or modifier in the development of polymers with specific optical or structural properties.

Basic Information

Product Name	1,3-Dioxane-2-Carboxaldehyde, 2,4-Dimethyl-, (2S-Cis)- (9Ci)
CAS No.	144404-98-8
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	(2S,4S)-2,4-Dimethyl-1,3-dioxane-2-carboxaldehyde; (2S-cis)-2,4-Dimethyl-1,3-dioxane-2-carboxaldehyde; 2,4-Dimethyl-1,3-dioxane-2-carboxaldehyde, (2S-cis)-; (cis)-2,4-Dimethyl-1,3-dioxane-2-carbaldehyde; (2S,4S)-2,4-Dimethyl-1,3-dioxane-2-carbaldehyde; 144404-98-8; (2S,4S)-2,4-Diméthyl-1,3-dioxanne-2-carbaldéhyde
EINECS	Contact for details

Quality Control

Our 1,3-Dioxane-2-Carboxaldehyde, 2,4-Dimethyl-, (2S-Cis)- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC and GC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This material is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.