Description

1,3-Dioxane-2-Carboxaldehyde, 2,4-Dimethyl-, (2R-Trans)- (9Ci) is a high-purity, chiral building block characterized by its specific stereochemistry and protected aldehyde functionality. This compound matters as a critical intermediate for synthesizing complex molecules in pharmaceutical and fine chemical research, offering precise control over stereochemical outcomes. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as asymmetric synthesis and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of chiral pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Fine Chemical Production: Serves as a versatile building block for creating specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & Industrial Research: Employed in methodological development for novel organic transformations and catalysis studies.
• Material Science: Potential precursor for designing chiral ligands, catalysts, or functional polymers.

Basic Information

Product Name	1,3-Dioxane-2-Carboxaldehyde, 2,4-Dimethyl-, (2R-Trans)- (9Ci)
CAS No.	144404-96-6
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	(2R,4R)-2,4-Dimethyl-1,3-dioxane-2-carboxaldehyde; (2R-trans)-2,4-Dimethyl-1,3-dioxane-2-carbaldehyde; 2,4-Dimethyl-1,3-dioxane-2-carboxaldehyde, (2R,4R)-; (2R,4R)-2,4-Dimethyl-1,3-dioxane-2-carbaldehyde; (R,R)-2,4-Dimethyl-1,3-dioxane-2-carboxaldehyde; 1,3-Dioxane-2-carboxaldehyde, 2,4-dimethyl-, (2R,4R)-; trans-2,4-Dimethyl-1,3-dioxane-2-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 1,3-Dioxane-2-Carboxaldehyde, 2,4-Dimethyl-, (2R-Trans)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.