Description

4-Bromo-2-Methoxy-1-Methylsulfanyl-Benzene is a versatile brominated aromatic building block featuring methoxy and methylthio substituents. This compound is valued for its unique electronic and steric properties, making it a critical intermediate in advanced organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a functionalized bromobenzene core.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the bromine atom serves as a handle for further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers due to its electron-donating substituents.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Custom Synthesis and Contract Manufacturing: Supplied to fine chemical companies for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	4-Bromo-2-Methoxy-1-Methylsulfanyl-Benzene
CAS No.	144369-82-4
Molecular Formula	C8H9BrOS
Molecular Weight	233.12 g/mol
Synonyms	1-Bromo-4-methoxy-2-(methylthio)benzene; 2-Methoxy-4-bromothioanisole; 4-Bromo-2-methoxythioanisole; 4-Bromo-2-(methylthio)anisole; Benzene, 1-bromo-4-methoxy-2-(methylthio)-; 2-Methoxy-4-bromo-1-methylsulfanylbenzene; 4-Bromo-2-methoxy-1-(methylthio)benzene
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Methoxy-1-Methylsulfanyl-Benzene is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.