Description

Ethanone, 1-(1-Ethyl-1H-Pyrrol-3-Yl)-2,2,2-Trifluoro- (9Ci) is a high-purity trifluoromethyl ketone derivative featuring a substituted pyrrole ring. This compound is a valuable specialty chemical intermediate prized for its unique molecular architecture, which combines electron-rich heterocyclic and electron-deficient trifluoromethyl ketone functionalities. It is primarily sought after by pharmaceutical R&D and agrochemical synthesis teams for constructing complex molecules.

Application

This advanced intermediate is designed for high-value synthesis applications across several industries:

• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and stability.
• Material Science Research: Employed in the development of specialty polymers, organic semiconductors, and liquid crystals due to its specific electronic properties.
• Organic Synthesis & Catalysis: Acts as a precursor or ligand in catalytic systems and as a scaffold for creating complex heterocyclic compounds in academic and industrial research.

Basic Information

Product Name	Ethanone, 1-(1-Ethyl-1H-Pyrrol-3-Yl)-2,2,2-Trifluoro- (9Ci)
CAS No.	144219-82-9
Molecular Formula	C8H8F3NO
Molecular Weight	191.15 g/mol
Synonyms	1-(1-Ethyl-1H-pyrrol-3-yl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(1-ethyl-1H-pyrrol-3-yl)ethanone; 1-(1-Ethylpyrrol-3-yl)-2,2,2-trifluoroethanone; 3-Trifluoroacetyl-1-ethylpyrrole; 1-Ethyl-3-(trifluoroacetyl)pyrrole; TFAP-Et; Trifluoroacetyl ethylpyrrole
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our advanced intermediates. Every batch of Ethanone, 1-(1-Ethyl-1H-Pyrrol-3-Yl)-2,2,2-Trifluoro- is analyzed using validated methods including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. Our quality system supports development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.