Description

(E)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Acrylic Acid is a high-value, functionalized acrylic acid derivative containing a pinacol boronate ester group, making it a versatile building block for advanced organic synthesis. This compound is essential for facilitating efficient carbon-carbon bond formation via cross-coupling reactions, offering chemists a powerful tool for constructing complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially those containing styrene or acrylic acid motifs.
• Agrochemical Synthesis: Used to construct complex bioactive molecules for next-generation herbicides, fungicides, and insecticides.
• Material Science & Polymer Chemistry: Serves as a functional monomer for creating advanced polymers with tailored properties, such as boronic acid-containing hydrogels for sensing applications.
• Organic Electronics: Employed in the synthesis of conjugated molecules and polymers for use in OLEDs, OFETs, and other electronic devices.
• Chemical Biology & Probe Development: Utilized to create molecular probes and bioconjugates that leverage the unique reactivity of the boronic ester group.
• Academic & Industrial R&D: A fundamental reagent for methodological development in synthetic organic chemistry and catalysis research.

Basic Information

Product Name	(E)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Acrylic Acid
CAS No.	144206-16-6
Molecular Formula	C11H19BO4
Molecular Weight	226.08 g/mol
Synonyms	trans-3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acrylic acid; (E)-3-(Pinacolatoboryl)acrylic Acid; 2-Propenoic acid, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, (2E)-; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acrylic acid; Pinacol (E)-3-boronatoacrylate; 144206-16-6; (E)-3-(Pinacolboronyl)acrylic Acid
EINECS	Contact for details

Quality Control

Our (E)-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Acrylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.