Description

3,4,4-Trifluoro-2,2-Dimethyl-But-3-Enoic Acid is a specialized fluorinated building block of significant interest in advanced organic synthesis. Its value lies in the unique reactivity and physicochemical properties imparted by the trifluoromethyl and carboxylic acid groups, enabling precise molecular modifications. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, particularly those requiring fluorinated motifs to enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine atoms can improve lipophilicity and environmental persistence.
• Material Science Precursor: Serves as a monomer or modifier in the development of specialty polymers and coatings with tailored surface properties and chemical resistance.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex molecules via reactions such as conjugate additions, cyclizations, and derivatizations.
• Fluorine Chemistry Research: An important compound for studying the effects of polyfluorination on reaction mechanisms and physical properties in organic chemistry.

Basic Information

Product Name	3,4,4-Trifluoro-2,2-Dimethyl-But-3-Enoic Acid
CAS No.	144194-00-3
Molecular Formula	C6H7F3O2
Molecular Weight	168.11 g/mol
Synonyms	3,4,4-Trifluoro-2,2-dimethylbut-3-enoic acid; 2,2-Dimethyl-3,4,4-trifluorobut-3-enoic Acid; 3-Butenoic acid, 3,4,4-trifluoro-2,2-dimethyl-; 3,4,4-Trifluoro-2,2-dimethyl-3-butenoic acid; TFDBA; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3,4,4-Trifluoro-2,2-Dimethyl-But-3-Enoic Acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.