Description

Indoxacarb Impurity 5 is a designated reference standard used in the analytical profiling and quality control of the insecticide Indoxacarb. This high-purity chemical impurity is critical for ensuring the safety, efficacy, and regulatory compliance of the active pharmaceutical ingredient (API). It is primarily required by agrochemical manufacturers, analytical laboratories, and regulatory bodies for method development, validation, and batch release testing.

Application

• Pharmaceutical Reference Standard: Serves as a certified impurity standard for the quantification and identification of related substances in Indoxacarb active ingredient batches.
• Analytical Method Development & Validation: Essential for developing and validating precise HPLC, GC, or LC-MS methods to monitor impurity profiles.
• Quality Assurance & Control (QA/QC): Used as a system suitability and calibration standard to ensure analytical procedures meet ICH and other regulatory guidelines for impurity limits.
• Regulatory Compliance & Documentation: Supports regulatory filings (e.g., with EPA, FDA) by providing definitive characterization data for impurity thresholds.
• Stability Studies: Employed to track the formation and levels of this specific degradation product under various storage conditions.
• Research & Development: Used in metabolic and environmental fate studies to understand the breakdown pathways of Indoxacarb.

Basic Information

Product Name	Indoxacarb Impurity 5
CAS No.	144171-39-1
Molecular Formula	C22H17ClF3N3O7
Molecular Weight	527.84 g/mol
Synonyms	Indoxacarb Related Compound 5; 7-Chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-(trifluoromethoxy)phenyl]amino]carbonyl]indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylic Acid Methyl Ester; Methyl (4aR,7S)-7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-(trifluoromethoxy)phenyl]amino]carbonyl]indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylate; DPX-JW062 Impurity 5; Indoxacarb Metabolite Reference Standard
EINECS	Contact for details

Quality Control

Our Indoxacarb Impurity 5 is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency. Each lot is characterized and released with a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Analytical methods are validated per ICH Q2(R1) guidelines, ensuring data integrity and regulatory compliance for its use as a reference standard.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere to prevent potential oxidation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual unspecified impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.