Description

(3R,4Z)-4-Ethylidenetetrahydro-5-Oxo-3-Furanacetaldehyde is a high-purity chiral furan derivative with a complex molecular architecture, serving as a critical advanced intermediate in sophisticated organic syntheses. Its value lies in its unique stereochemistry and functional groups, which enable the construction of complex molecules with high precision and efficiency. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty fine chemical industries.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where specific stereochemistry is required for bioactivity.
• Fine Chemical Production: Serves as a precursor in the manufacture of complex flavors, fragrances, and other high-value specialty chemicals.
• Academic & Industrial R&D: A valuable reagent for methodological development in asymmetric synthesis and catalysis studies within chemistry laboratories.
• Material Science Research: Potential monomer or precursor for developing novel polymers with specific functional properties.

Basic Information

Product Name	(3R,4Z)-4-Ethylidenetetrahydro-5-Oxo-3-Furanacetaldehyde
CAS No.	144128-26-7
Molecular Formula	C8H10O3
Molecular Weight	154.16 g/mol
Synonyms	(3R,4Z)-4-Ethylidene-5-oxotetrahydrofuran-3-acetaldehyde; 4-Ethylidene-5-oxotetrahydro-3-furanacetaldehyde, (3R,4Z)-; Tetrahydro-5-oxo-4-ethylidene-3-furanacetaldehyde; (3R,4Z)-4-Ethylidene-5-oxotetrahydrofuran-3-acetaldehyde; 3-Furanacetaldehyde, 4-ethylidenetetrahydro-5-oxo-, (3R,4Z)-; (3R,4Z)-4-Ethylidene-5-oxo-tetrahydrofuran-3-acetaldehyde
EINECS	Contact for details

Quality Control

Our (3R,4Z)-4-Ethylidenetetrahydro-5-Oxo-3-Furanacetaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be sensitive to moisture and oxidation; consider storage under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.