Description

5-Indolylboronic Acid is a high-purity organoboron building block essential for modern synthetic chemistry, particularly in cross-coupling reactions. Its primary value lies in enabling the efficient and selective construction of complex indole-containing molecules, which are privileged scaffolds in medicinal chemistry. This compound is critically needed by pharmaceutical R&D teams, agrochemical researchers, and advanced material scientists for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially those targeting central nervous system disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators that incorporate the indole moiety.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and enzyme inhibitors for studying biological pathways and protein function.
• Academic & Contract Research: A staple reagent in university and CRO laboratories for methodological development in synthetic organic chemistry.
• Scale-up & Process Chemistry: Suitable for kilogram-scale production under GMP-like conditions for late-stage clinical trial material manufacturing.

Basic Information

Product Name	5-Indolylboronic Acid
CAS No.	144104-59-6
Molecular Formula	C8H8BNO2
Molecular Weight	160.97 g/mol
Synonyms	5-Indoleboronic Acid; 1H-Indol-5-ylboronic Acid; (1H-Indol-5-yl)boronic Acid; 5-Boron-1H-indole; Indole-5-boronic Acid; 5-Indolyl-B(OH)2; 5-Boronoindole
EINECS	Contact for details

Quality Control

Our 5-Indolylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements for research and development. We provide full traceability and Certificates of Analysis (COA) are available for every shipment. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.