Description

(4-Formyl-Phenyl)-Carbamic Acid tert-Butyl Ester is a protected aldehyde derivative of an aromatic amine, serving as a versatile and critical building block in advanced organic synthesis. Its value lies in the orthogonal protection of the amine group and the reactive formyl functionality, enabling precise, multi-step synthetic sequences. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing complex molecules such as active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates, particularly those containing aromatic amine and aldehyde pharmacophores.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and plant growth regulators.
• Peptide Mimetics & Conjugates: Used in the development of peptide-based drugs and bioconjugates where selective deprotection is required.
• Material Science Research: Monomer or precursor for synthesizing specialty polymers, dendrimers, and organic frameworks with tailored properties.
• Chemical Biology Probes: Serves as a scaffold for creating fluorescent tags, affinity labels, and other molecular probes.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific research and development projects.

Basic Information

Product Name	(4-Formyl-Phenyl)-Carbamic Acid tert-Butyl Ester
CAS No.	144072-30-0
Molecular Formula	C12H15NO3
Molecular Weight	221.25 g/mol
Synonyms	4-[(tert-Butoxycarbonyl)amino]benzaldehyde; N-Boc-4-aminobenzaldehyde; tert-Butyl (4-formylphenyl)carbamate; 4-(Boc-amino)benzaldehyde; 4-Formylphenylcarbamic Acid tert-Butyl Ester; Boc-4-Abz-OH; p-Formyl-N-Boc-aniline; N-(tert-Butoxycarbonyl)-4-aminobenzaldehyde
EINECS	Contact for details

Quality Control

Our (4-Formyl-Phenyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under an inert atmosphere when appropriate to minimize oxidation risk. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.