Description

3-Pyridinecarboxaldehyde,5-(Trimethylsilyl)-(9Ci) is a specialized organosilicon derivative of pyridinecarboxaldehyde, serving as a high-value synthetic intermediate. Its core value lies in the strategic incorporation of a trimethylsilyl group, which provides steric bulk and modifies electronic properties for advanced organic synthesis. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to construct complex heterocyclic scaffolds and functionalized pyridine systems. The CAS number for this compound is 144056-15-5.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in creating libraries of nitrogen-containing heterocycles for medicinal chemistry.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the pyridine core for biological activity.
• Ligand Precursor: Serves as a starting material for the preparation of sophisticated ligands used in catalysis and material science.
• Functional Material Research: Employed in the development of organic semiconductors, light-emitting materials, and other advanced functional molecules.
• Cross-Coupling Reactions: The aldehyde and silyl groups make it a versatile substrate for various palladium-catalyzed and other metal-mediated coupling reactions.
• Academic & R&D: A valuable reagent for methodological development in organic synthesis and exploring new reaction pathways.

Basic Information

Product Name	3-Pyridinecarboxaldehyde,5-(Trimethylsilyl)-(9Ci)
CAS No.	144056-15-5
Molecular Formula	C9H13NOSi
Molecular Weight	179.30 g/mol
Synonyms	5-(Trimethylsilyl)pyridine-3-carboxaldehyde; 3-Formyl-5-(trimethylsilyl)pyridine; 5-(Trimethylsilyl)nicotinaldehyde; 5-Trimethylsilylnicotinaldehyde; 3-Pyridinecarboxaldehyde, 5-(trimethylsilyl)-; 144056-15-5; 5-Trimethylsilyl-3-pyridinecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarboxaldehyde,5-(Trimethylsilyl)-(9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality system is designed to meet the stringent requirements of R&D and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent oxidation and moisture uptake. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.