Description

Cyclopropanebutanol, 2,2-Difluoro- (9Ci) is a specialized fluorinated organic building block characterized by its unique cyclopropane ring and terminal alcohol functionality. This compound matters as a high-value intermediate for synthesizing complex molecules, offering chemists a versatile handle for introducing fluorinated cyclopropane motifs, which are prized in modern drug discovery for their ability to modulate metabolic stability and lipophilicity. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries, as well as by fine chemical manufacturers focused on advanced material science.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorinated cyclopropane unit can enhance biological activity and environmental persistence profiles.
• Liquid Crystal & Advanced Material Precursor: Serves as a building block for fluorinated components in liquid crystal displays (LCDs) and other specialty polymers requiring specific dielectric or surface properties.
• Organic Synthesis & Process Chemistry: Employed in academic and industrial laboratories for method development, catalysis studies, and the scalable synthesis of complex natural product analogs.
• Fluorine Chemistry Research: An important reagent for investigating structure-activity relationships (SAR) and the effects of fluorination on molecular conformation and reactivity.

Basic Information

Product Name	Cyclopropanebutanol, 2,2-Difluoro- (9Ci)
CAS No.	143952-26-5
Molecular Formula	C7H12F2O
Molecular Weight	150.17 g/mol
Synonyms	2,2-Difluorocyclopropanebutanol; 4-(2,2-Difluorocyclopropyl)butan-1-ol; Butan-1-ol, 4-(2,2-difluorocyclopropyl)-; 4-(2,2-Difluorocyclopropyl)-1-butanol
EINECS	Contact for details

Quality Control

Our Cyclopropanebutanol, 2,2-Difluoro- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency suitable for research and process development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Standard Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.