Description

Oxiranecarboxaldehyde, 3-(Trimethylsilyl)-, (2S-Trans)- (9Ci) is a high-value, chiral organosilicon building block featuring a reactive epoxide and aldehyde functional group. This compound is essential for the stereoselective synthesis of complex molecules, enabling the introduction of both protected hydroxyl and formyl moieties in a single, controlled step. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the asymmetric synthesis of complex drug candidates, particularly in oncology and antiviral research.
• Agrochemical Synthesis: Used in the development of enantiomerically pure active ingredients for next-generation herbicides and pesticides.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the production of specialty silicones and epoxy-based polymers with tailored properties.
• Ligand and Catalyst Development: Employed in the construction of novel chiral ligands and organocatalysts for asymmetric catalysis.
• Academic and R&D: A valuable tool in organic chemistry research for methodology development and exploring new reaction pathways.
• Fine Chemical Production: Integral to the multi-step synthesis of high-value flavors, fragrances, and other specialty chemicals requiring precise stereochemistry.

Basic Information

Product Name	Oxiranecarboxaldehyde, 3-(Trimethylsilyl)-, (2S-Trans)- (9Ci)
CAS No.	143800-08-2
Molecular Formula	C7H14O2Si
Molecular Weight	158.27 g/mol
Synonyms	(2S,3S)-3-(Trimethylsilyl)oxiranecarboxaldehyde; (2S-trans)-3-(Trimethylsilyl)glycidaldehyde; (2S,3S)-3-(Trimethylsilyl)glycidic aldehyde; 3-(Trimethylsilyl)-D-glycidaldehyde; (2S,3S)-Epoxy-3-(trimethylsilyl)propanal; (2S,3S)-3-(Trimethylsilyl)oxirane-2-carbaldehyde; TMS-Glycidaldehyde (chiral); (S,S)-3-(Trimethylsilyl)glycidaldehyde
EINECS	Contact for details

Quality Control

Our production of Oxiranecarboxaldehyde, 3-(Trimethylsilyl)-, (2S-Trans)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by comprehensive analytical techniques including chiral HPLC, NMR, and GC-MS. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry, well-ventilated area. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or ambient light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.