Description

3-(4-Fluorophenyl)Cyclobutan-1-One is a high-value, synthetically versatile fluorinated cyclobutanone derivative. This compound serves as a critical pharmaceutical intermediate and advanced building block for the development of novel active ingredients. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate its unique strained ring and fluorine-substituted aromatic system into new molecular entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides, where the fluorophenyl group can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a building block for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic electronic materials due to its rigid cyclobutane core and fluorine atom.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-(4-Fluorophenyl)Cyclobutan-1-One
CAS No.	143589-42-8
Molecular Formula	C10H9FO
Molecular Weight	164.18 g/mol
Synonyms	3-(4-Fluorophenyl)cyclobutanone; 4-Fluorophenylcyclobutanone; 1-(4-Fluorophenyl)cyclobutan-3-one; 3-(p-Fluorophenyl)cyclobutanone; 4-Fluorobenzenecyclobutanone; Cyclobutanone, 3-(4-fluorophenyl)-; 143589-42-8
EINECS	Contact for details

Quality Control

Our production of 3-(4-Fluorophenyl)Cyclobutan-1-One adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.