Description

1-(4-Bromophenyl)Cyclopentanecarbonitrile is a versatile brominated aromatic nitrile building block, valued for its unique cyclopentane-fused structure that introduces steric and electronic complexity. This compound is essential for advanced organic synthesis, particularly in constructing complex molecular scaffolds for pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or as kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bromophenyl moiety for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in asymmetric catalysis and transition metal complexes.
• Material Science Precursor: Employed in the synthesis of organic semiconductors, liquid crystals, or advanced polymers where the bromine atom allows for further functionalization via cross-coupling reactions.
• Chemical Biology Probe Synthesis: Utilized to build molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis projects and scale-up services under cGMP or ISO standards.

Basic Information

Item	Details
Product Name	1-(4-Bromophenyl)Cyclopentanecarbonitrile
CAS No.	143328-19-2
Molecular Formula	C12H12BrN
Molecular Weight	250.14 g/mol
Synonyms	4-Bromo-α-(cyclopentylidene)benzenecetonitrile; (4-Bromophenyl)cyclopentanecarbonitrile; 1-(p-Bromophenyl)cyclopentanecarbonitrile; 1-Cyclopentyl-1-(4-bromophenyl)methanenitrile; α-Cyclopentyl-4-bromobenzeneacetonitrile; p-Bromophenylcyclopentanecarbonitrile
EINECS	Contact for details

Quality Control

Our 1-(4-Bromophenyl)Cyclopentanecarbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment. Our quality commitment aligns with ISO 9001 standards, and we can support development projects requiring ICH stability guidelines or regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.