Description

[1,2,4]Triazolo[1,5-A]Pyridine-5-Carboxaldehyde (9Ci) is a versatile and high-value heterocyclic building block, specifically a fused triazolopyridine derivative bearing a reactive aldehyde functional group. This compound is of significant importance in advanced organic synthesis and pharmaceutical research, serving as a key precursor for constructing complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry, ligand synthesis, and the development of novel functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: The aldehyde group allows for facile condensation reactions to create novel chelating ligands for metal catalysis and coordination chemistry.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of organic electronic materials, such as OLEDs or conductive polymers.
• Chemical Biology Probe Synthesis: Utilized to create tagged molecules or affinity probes for studying biological targets and pathways.
• Academic & Contract Research: Employed in universities and CROs for fundamental research in heterocyclic chemistry and method development.

Basic Information

Item	Detail
Product Name	[1,2,4]Triazolo[1,5-A]Pyridine-5-Carboxaldehyde (9Ci)
CAS No.	143307-82-8
Molecular Formula	C7H5N3O
Molecular Weight	147.13 g/mol
Synonyms	1,2,4-Triazolo[1,5-a]pyridine-5-carboxaldehyde; 5-Formyl-[1,2,4]triazolo[1,5-a]pyridine; [1,2,4]Triazol[1,5-a]pyridin-5-carbaldehyd; Triazolopyridine-5-carboxaldehyde; 1,2,4-Triazolo[1,5-a]pyridine-5-carbaldehyde; 143307-82-8 (CAS); 5-Carbaldehyde-[1,2,4]triazolo[1,5-a]pyridine
EINECS	Contact for details

Quality Control

Our [1,2,4]Triazolo[1,5-A]Pyridine-5-Carboxaldehyde is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to handle and store the material under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.