Description

Isoxazolo[3,2-C][1,4]Oxazine-3-Carboxaldehyde, Hexahydro-, trans- (9Ci) CAS NO 143262-78-6 is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key chiral intermediate for constructing complex molecular architectures with high stereochemical control. Pharmaceutical and agrochemical research organizations need it for the development of novel active ingredients, particularly in medicinal chemistry programs targeting new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral scaffold in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective targets.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its complex fused-ring structure.
• Asymmetric Catalysis Ligand Precursor: Acts as a starting material for the synthesis of novel chiral ligands used in asymmetric hydrogenation and other catalytic transformations.
• Academic & Industrial R&D: Employed in methodological studies and the exploration of new chemical space within heterocyclic and isoxazoline chemistry.
• Fine Chemical Production: Utilized in the custom synthesis of high-value, low-volume specialty chemicals for various technology sectors.

Basic Information

Product Name	Isoxazolo[3,2-C][1,4]Oxazine-3-Carboxaldehyde, Hexahydro-, trans- (9Ci)
CAS No.	143262-78-6
Molecular Formula	C7H9NO3
Molecular Weight	155.15 g/mol
Synonyms	trans-Hexahydroisoxazolo[3,2-c][1,4]oxazine-3-carboxaldehyde; (3R,3aR,6aS)-Tetrahydro-2H-furo[3,2-b]pyrrole-3-carboxaldehyde (related stereoisomer); Isoxazolo-oxazine carboxaldehyde; Hexahydroisoxazoloxazine carbaldehyde; Bicyclic isoxazoline aldehyde; Fused isoxazoline-oxazine intermediate; Chiral isoxazoline building block
EINECS	Contact for details

Quality Control

Every batch of Isoxazolo[3,2-C][1,4]Oxazine-3-Carboxaldehyde, Hexahydro-, trans- (9Ci) is produced and tested under a strict quality management system. We ensure compliance with the high-purity standards required for pharmaceutical R&D and advanced synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This product is easily oxidized and light-sensitive; allow it to reach room temperature in the sealed, protected container before use to minimize moisture ingress and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.