Description

(5-Methyl-3-Trifluoromethyl-1H-Pyrrol-2-Yl)-Phenyl-Methanone is a high-value, fluorinated pyrrole derivative with a distinct ketone functional group. This compound is a crucial advanced pharmaceutical intermediate (API intermediate) and a versatile building block in modern synthetic organic chemistry. It is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Active Ingredient Development: Serves as a core structure for creating new-generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its unique fluorinated aromatic system.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, cyclizations, and as a precursor for more complex heterocyclic compounds in academic and industrial research.
• Fluorine Chemistry Studies: Acts as a model compound for studying the influence of the trifluoromethyl group on the reactivity and physicochemical properties of pyrrole systems.

Basic Information

Product Name	(5-Methyl-3-Trifluoromethyl-1H-Pyrrol-2-Yl)-Phenyl-Methanone
CAS No.	142991-72-8
Molecular Formula	C13H10F3NO
Molecular Weight	253.22 g/mol
Synonyms	2-Benzoyl-5-methyl-3-(trifluoromethyl)-1H-pyrrole; 1H-Pyrrole-2-methanone, 5-methyl-3-(trifluoromethyl)-, phenyl-; Phenyl(5-methyl-3-(trifluoromethyl)-1H-pyrrol-2-yl)methanone; (5-Methyl-3-trifluoromethyl-1H-pyrrol-2-yl)-phenyl-methanone; 5-Methyl-3-trifluoromethyl-1H-pyrrole-2-carboxylic acid phenyl ester (common misnomer); TFMPK derivative
EINECS	Contact for details

Quality Control

Our production of (5-Methyl-3-Trifluoromethyl-1H-Pyrrol-2-Yl)-Phenyl-Methanone adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. The final product is characterized and released according to a comprehensive specification sheet. Certificates of Analysis (COA) documenting identity, purity (typically ≥97% by HPLC), and impurity profiles are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.