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Diacetato[(S)-(-)-2,2'-Bis(Diphenylphosphino)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Binaphthy]Ruthenium(Ii) CAS NO 142962-95-6
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CAS No.:142962-95-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Diacetato[(S)-(-)-2,2'-Bis(Diphenylphosphino)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Binaphthy]Ruthenium(II) is a high-value, chiral ruthenium complex widely recognized for its exceptional catalytic performance in asymmetric synthesis. This compound matters because it serves as a highly efficient and selective catalyst for key organic transformations, enabling the production of enantiomerically pure intermediates critical for advanced pharmaceuticals and fine chemicals. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-performance catalysts for complex hydrogenation and transfer hydrogenation reactions.
Application
- Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of ketones, imines, and olefins to produce chiral alcohols, amines, and other building blocks.
- Pharmaceutical Intermediate Synthesis: Key catalyst in the production of enantiomerically pure active pharmaceutical ingredients (APIs) for drugs targeting central nervous system, cardiovascular, and metabolic diseases.
- Transfer Hydrogenation Reactions: Used in reactions where hydrogen donors like isopropanol or formic acid are employed instead of molecular hydrogen.
- Fine Chemical Manufacturing: Enables the synthesis of complex chiral molecules for flavors, fragrances, and advanced materials.
- Academic and Industrial R&D: A valuable tool for method development and exploring new asymmetric catalytic processes in laboratory and pilot-scale settings.
- Agrochemical Synthesis: Used in the production of chiral herbicides, fungicides, and plant growth regulators.
Basic Information
| Product Name | Diacetato[(S)-(-)-2,2'-Bis(Diphenylphosphino)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Binaphthy]Ruthenium(II) |
| CAS No. | 142962-95-6 |
| Molecular Formula | C48H46O4P2Ru |
| Molecular Weight | 855.90 g/mol |
| Synonyms | (S)-(-)-Ru(OAc)2(BINAP); (S)-Ru(OAc)2(H8-BINAP); Ruthenium(II) acetate (S)-H8-BINAP complex; (S)-H8-BINAP-Ru(OAc)2; [Ru((S)-H8-binap)(OAc)2]; (S)-2,2'-Bis(diphenylphosphino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl ruthenium(II) diacetate; (S)-H8-BINAP Ru diacetate; Ru-(S)-H8-BINAP diacetate |
| EINECS | Contact for details |
Quality Control
Our Diacetato[(S)-(-)-2,2'-Bis(Diphenylphosphino)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Binaphthy]Ruthenium(II) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric excess, ensuring compliance with stringent industry standards for catalytic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific performance characteristics is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, the container must be kept sealed in a cool, dry place and only opened in a moisture-free, inert environment.
Specification
| Item | Specification |
|---|---|
| Appearance | Orange to red-brown crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Chiral Purity (HPLC) | ≥ 99.0% ee |
| Ruthenium Content | 11.5 - 12.5 % |
| Solubility | Soluble in dichloromethane, toluene; slightly soluble in methanol |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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