Description

Triptoquinone A CAS NO 142950-86-5 is a bioactive diterpenoid quinone compound isolated from the traditional medicinal plant *Tripterygium wilfordii* (Thunder God Vine). This compound is of significant interest for its potent and selective biological activities, particularly as a modulator of inflammatory pathways. It serves as a critical high-purity reference standard and research-grade biochemical for pharmaceutical R&D and advanced life science studies. Key industrial users include biotechnology firms, academic research institutions, and contract research organizations (CROs) focused on immunology, oncology, and novel therapeutic discovery.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of herbal extracts and finished products in quality control laboratories.
• Bioactive Lead Compound: Serves as a starting point or intermediate in the research and development of new anti-inflammatory and immunomodulatory drugs.
• Mechanistic Studies: Employed in in vitro and in vivo research to investigate signaling pathways related to NF-κB and other inflammatory mediators.
• Natural Product Chemistry: Acts as a key marker compound for the standardization and authentication of *Tripterygium wilfordii* extracts.
• Biochemical Research: Utilized in high-throughput screening assays and target validation studies within academic and industrial R&D settings.

Basic Information

Product Name	Triptoquinone A
CAS No.	142950-86-5
Molecular Formula	C₂₀H₂₄O₄
Molecular Weight	328.40 g/mol
Synonyms	Triptoquinone A; (4bS,8aR)-4b,5,6,7,8,8a,9,10-Octahydro-4b,8,8-trimethyl-2(1H)-phenanthrenone; 1,4-Phenanthrenedione, 4b,5,6,7,8,8a,9,10-octahydro-4b,8,8-trimethyl-, (4bS,8aR)-; Triptoquinone-A; Celastrol derivative; Quinone diterpenoid from Tripterygium wilfordii
EINECS	Contact for details

Quality Control

Every batch of our Triptoquinone A is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. We provide comprehensive analytical data including HPLC purity, NMR, and MS confirmation. A Certificate of Analysis (COA) detailing all specifications and test results is supplied with each shipment. Our quality system supports research requiring materials traceable to authenticated reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere for long-term stability. The compound is light-sensitive (store away from light) and should be handled in a controlled environment to prevent degradation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.