Description

5-Ethynyl-2-Methoxy-Benzaldehyde is a versatile aromatic aldehyde building block featuring both an aldehyde and an ethynyl functional group. This unique bifunctional structure makes it a critical intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients and by material scientists developing specialty polymers and ligands.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and oncology research programs.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers, resins, and advanced organic frameworks (MOFs/COFs).
• Ligand and Catalyst Development: The alkyne and aldehyde groups allow for the construction of complex chelating ligands for catalytic and sensing applications.
• Chemical Research: Employed in academic and industrial labs for methodological development in organic synthesis, including click chemistry and Sonogashira coupling reactions.
• Fine Chemical Production: An intermediate in the multi-step synthesis of dyes, flavors, and fragrances.

Basic Information

Product Name	5-Ethynyl-2-Methoxy-Benzaldehyde
CAS No.	142686-55-3
Molecular Formula	C10H8O2
Molecular Weight	160.17 g/mol
Synonyms	2-Methoxy-5-ethynylbenzaldehyde; 5-Ethynyl-2-methoxybenzaldehyde; 5-Ethynyl-o-anisaldehyde; 2-Methoxy-5-ethynylbenzenecarboxaldehyde; Benzaldehyde, 5-ethynyl-2-methoxy-
EINECS	Contact for details

Quality Control

Our 5-Ethynyl-2-Methoxy-Benzaldehyde is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming it meets the agreed specifications for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.