Description

2H-Pyran-2-One,Tetrahydro-6-Methyl-3-(1-Methylethyl)-,(3R,6S)-Rel-(9Ci) is a specific stereoisomer of a tetrahydro-6-methyl-3-isopropyl-2H-pyran-2-one, a chiral lactone building block of significant interest in fine chemical synthesis. This compound matters for its role as a key intermediate in the production of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where stereochemical purity is critical for biological activity. Industries that require high-purity chiral synthons for research, process development, and commercial manufacturing will find this material essential.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting neurological or metabolic pathways.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the specific stereochemistry influences efficacy and environmental profile.
• Flavor & Fragrance Chemistry: Acts as a precursor for the synthesis of complex lactone-based aroma compounds, contributing to creamy, fruity, or coconut-like notes.
• Organic Synthesis Research: A valuable reagent for academic and industrial R&D in developing new asymmetric synthesis methodologies and exploring novel chemical spaces.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, including liquid crystals, advanced polymers, and performance materials requiring specific stereocenters.

Basic Information

Product Name	2H-Pyran-2-One,Tetrahydro-6-Methyl-3-(1-Methylethyl)-,(3R,6S)-Rel-(9Ci)
CAS No.	142636-31-5
Molecular Formula	C9H16O2
Molecular Weight	156.22 g/mol
Synonyms	(3R,6S)-rel-6-Methyl-3-(1-methylethyl)tetrahydro-2H-pyran-2-one; (-)-Massoia lactone (rel form); 6-Methyl-3-isopropyl-5,6-dihydro-2H-pyran-2-one; Tetrahydro-6-methyl-3-(1-methylethyl)-2H-pyran-2-one; Dihydro-6-methyl-3-(isopropyl)-2H-pyran-2(3H)-one; (rel)-(3R,6S)-6-Methyl-3-isopropyltetrahydro-2H-pyran-2-one; 2H-Pyran-2-one, tetrahydro-6-methyl-3-(1-methylethyl)-, (3R,6S)-rel-
EINECS	Contact for details

Quality Control

Our production of 2H-Pyran-2-One,Tetrahydro-6-Methyl-3-(1-Methylethyl)-,(3R,6S)-Rel-(9Ci) adheres to stringent quality management systems to ensure batch-to-batch consistency and high stereochemical purity. The material undergoes rigorous analytical testing, including chiral HPLC, GC, and NMR, to confirm identity, purity, and isomeric composition. Certificates of Analysis (COA) detailing all specifications are provided with each shipment, supporting compliance in cGMP and ISO 9001 environments for advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (for specified isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.